Brain Development Research Program

Dr. Elliott Sherr and the Brain Developmental Research Program are interested in elucidating the genetic basis and clinical manifestations of neurodevelopmental disorders of cognition and epilepsy, with a particular focus in: agenesis of the corpus callosum (ACC), periventricular nodular heterotopia (PVNH), polymicrogyria (PMG), Dandy Walker malformations (DM) and cerebellar hypolasia (CBLH). We are studying the clinical, genetic, and radiographic features of these disorders to better understand the problems that individuals affected by these disorders are likely to face. Likewise, Dr. Sherr’s research team is studying associated disorders such as Aicardi Syndrome. The goal of our research is to develop a better understanding of the underlying genetic causes as a foundation for devising better treatments for these groups of patients.